node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCAN_1373 | HCAN_1374 | HCAN_1373 | HCAN_1374 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Conserved hypothetical protein. | 0.815 |
HCAN_1373 | HCAN_1375 | HCAN_1373 | HCAN_1375 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Conserved hypothetical protein. | 0.815 |
HCAN_1373 | hemA | HCAN_1373 | HCAN_1372 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.815 |
HCAN_1373 | hemC | HCAN_1373 | HCAN_1369 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.782 |
HCAN_1373 | hisD | HCAN_1373 | HCAN_1376 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.811 |
HCAN_1373 | proS | HCAN_1373 | HCAN_1371 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.815 |
HCAN_1374 | HCAN_1373 | HCAN_1374 | HCAN_1373 | Conserved hypothetical protein. | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.815 |
HCAN_1374 | HCAN_1375 | HCAN_1374 | HCAN_1375 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.815 |
HCAN_1374 | hemA | HCAN_1374 | HCAN_1372 | Conserved hypothetical protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.815 |
HCAN_1374 | hemC | HCAN_1374 | HCAN_1369 | Conserved hypothetical protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.683 |
HCAN_1374 | hisD | HCAN_1374 | HCAN_1376 | Conserved hypothetical protein. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.810 |
HCAN_1374 | proS | HCAN_1374 | HCAN_1371 | Conserved hypothetical protein. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.815 |
HCAN_1375 | HCAN_1373 | HCAN_1375 | HCAN_1373 | Conserved hypothetical protein. | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.815 |
HCAN_1375 | HCAN_1374 | HCAN_1375 | HCAN_1374 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.815 |
HCAN_1375 | hemA | HCAN_1375 | HCAN_1372 | Conserved hypothetical protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.815 |
HCAN_1375 | hemC | HCAN_1375 | HCAN_1369 | Conserved hypothetical protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.683 |
HCAN_1375 | hisD | HCAN_1375 | HCAN_1376 | Conserved hypothetical protein. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.810 |
HCAN_1375 | proS | HCAN_1375 | HCAN_1371 | Conserved hypothetical protein. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.814 |
gltX | gltX-2 | HCAN_0174 | HCAN_1187 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.889 |
gltX | hemA | HCAN_0174 | HCAN_1372 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.937 |