node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCA_001696535_01873 | guaA | GCA_001696535_01873 | GCA_001696535_00783 | Unannotated protein. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.747 |
GCA_001696535_01873 | secF-2 | GCA_001696535_01873 | GCA_001696535_01356 | Unannotated protein. | Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.437 |
GCA_001696535_01873 | tgt | GCA_001696535_01873 | GCA_001696535_00219 | Unannotated protein. | Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...] | 0.749 |
GCA_001696535_01873 | truB | GCA_001696535_01873 | GCA_001696535_03752 | Unannotated protein. | Unannotated protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.443 |
TypA | guaA | GCA_001696535_04261 | GCA_001696535_00783 | Unannotated protein. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.772 |
TypA | secF-2 | GCA_001696535_04261 | GCA_001696535_01356 | Unannotated protein. | Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.427 |
TypA | tgt | GCA_001696535_04261 | GCA_001696535_00219 | Unannotated protein. | Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...] | 0.521 |
guaA | GCA_001696535_01873 | GCA_001696535_00783 | GCA_001696535_01873 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein. | 0.747 |
guaA | TypA | GCA_001696535_00783 | GCA_001696535_04261 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein. | 0.772 |
guaA | ribB | GCA_001696535_00783 | GCA_001696535_02682 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.747 |
guaA | tgt | GCA_001696535_00783 | GCA_001696535_00219 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...] | 0.696 |
guaA | thyA | GCA_001696535_00783 | GCA_001696535_01272 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.437 |
guaA | truB | GCA_001696535_00783 | GCA_001696535_03752 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.968 |
queA | secF-2 | GCA_001696535_00220 | GCA_001696535_01356 | Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.517 |
queA | tgt | GCA_001696535_00220 | GCA_001696535_00219 | Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...] | 0.998 |
queA | truB | GCA_001696535_00220 | GCA_001696535_03752 | Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Unannotated protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.513 |
queA | uppP | GCA_001696535_00220 | GCA_001696535_03899 | Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Unannotated protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.525 |
ribB | guaA | GCA_001696535_02682 | GCA_001696535_00783 | Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.747 |
ribB | secD | GCA_001696535_02682 | GCA_001696535_00344 | Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.489 |
ribB | secF-2 | GCA_001696535_02682 | GCA_001696535_01356 | Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.646 |