node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFD55850.1 | SFD74613.1 | SAMN02745121_00605 | SAMN02745121_01322 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Hypothetical protein. | 0.845 |
SFD55850.1 | SFD92117.1 | SAMN02745121_00605 | SAMN02745121_02208 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Co-chaperonin GroES (HSP10). | 0.698 |
SFD55850.1 | dnaJ | SAMN02745121_00605 | SAMN02745121_01676 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.947 |
SFD55850.1 | dnaJ-2 | SAMN02745121_00605 | SAMN02745121_02246 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.946 |
SFD55850.1 | groL | SAMN02745121_00605 | SAMN02745121_01847 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.829 |
SFD55850.1 | groS | SAMN02745121_00605 | SAMN02745121_01846 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.729 |
SFD55850.1 | grpE | SAMN02745121_00605 | SAMN02745121_02248 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.973 |
SFD65734.1 | SFD74613.1 | SAMN02745121_00969 | SAMN02745121_01322 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Hypothetical protein. | 0.845 |
SFD65734.1 | SFD92117.1 | SAMN02745121_00969 | SAMN02745121_02208 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Co-chaperonin GroES (HSP10). | 0.698 |
SFD65734.1 | dnaJ | SAMN02745121_00969 | SAMN02745121_01676 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.946 |
SFD65734.1 | dnaJ-2 | SAMN02745121_00969 | SAMN02745121_02246 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.947 |
SFD65734.1 | groL | SAMN02745121_00969 | SAMN02745121_01847 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.848 |
SFD65734.1 | groS | SAMN02745121_00969 | SAMN02745121_01846 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.767 |
SFD65734.1 | grpE | SAMN02745121_00969 | SAMN02745121_02248 | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.974 |
SFD74613.1 | SFD55850.1 | SAMN02745121_01322 | SAMN02745121_00605 | Hypothetical protein. | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | 0.845 |
SFD74613.1 | SFD65734.1 | SAMN02745121_01322 | SAMN02745121_00969 | Hypothetical protein. | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | 0.845 |
SFD74613.1 | SFD92117.1 | SAMN02745121_01322 | SAMN02745121_02208 | Hypothetical protein. | Co-chaperonin GroES (HSP10). | 0.737 |
SFD74613.1 | SFD92770.1 | SAMN02745121_01322 | SAMN02745121_02247 | Hypothetical protein. | Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. | 0.845 |
SFD74613.1 | dnaJ | SAMN02745121_01322 | SAMN02745121_01676 | Hypothetical protein. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.672 |
SFD74613.1 | dnaJ-2 | SAMN02745121_01322 | SAMN02745121_02246 | Hypothetical protein. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.672 |