STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFD91721.1Phosphotransferase system, enzyme I, PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (607 aa)    
Predicted Functional Partners:
SFD91740.1
Phosphocarrier protein.
 
 0.999
hprK
Hpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
   
 0.954
SFD91754.1
PTS system, mannose-specific IIA component.
 
   
 0.840
SFE07641.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.823
SFE29151.1
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit.
    
  0.823
SFD91767.1
UPF0042 nucleotide-binding protein; Displays ATPase and GTPase activities.
     
 0.810
SFE40264.1
2-oxoisovalerate dehydrogenase E1 component.
  
 
 0.796
SFD91714.1
Pimeloyl-ACP methyl ester carboxylesterase.
       0.773
SFD91695.1
WD40-like Beta Propeller Repeat.
       0.757
hpf
SSU ribosomal protein S30P /sigma 54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
  
 0.706
Your Current Organism:
Nannocystis exedens
NCBI taxonomy Id: 54
Other names: ATCC 25963, DSM 71, N. exedens
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