node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFD64669.1 | SFE95765.1 | SAMN02745121_00892 | SAMN02745121_06257 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein. | 0.714 |
SFD64669.1 | SFF00728.1 | SAMN02745121_00892 | SAMN02745121_06470 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Nicotinamide-nucleotide amidase; Belongs to the CinA family. | 0.457 |
SFD64669.1 | SFF17364.1 | SAMN02745121_00892 | SAMN02745121_07323 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Amino acid adenylation domain-containing protein. | 0.521 |
SFD64669.1 | SFF19357.1 | SAMN02745121_00892 | SAMN02745121_07429 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Amino acid adenylation domain-containing protein. | 0.521 |
SFD64669.1 | SFF19374.1 | SAMN02745121_00892 | SAMN02745121_07430 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Amino acid adenylation domain-containing protein. | 0.521 |
SFD64669.1 | SFF36086.1 | SAMN02745121_00892 | SAMN02745121_08376 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Amino acid adenylation domain-containing protein. | 0.836 |
SFD64669.1 | SFF50914.1 | SAMN02745121_00892 | SAMN02745121_09234 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphopantetheine attachment site. | 0.517 |
SFD64669.1 | guaA | SAMN02745121_00892 | SAMN02745121_00654 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.551 |
SFD64669.1 | guaB | SAMN02745121_00892 | SAMN02745121_00655 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.883 |
SFE95747.1 | SFE95765.1 | SAMN02745121_06256 | SAMN02745121_06257 | Hypothetical protein. | Hypothetical protein. | 0.773 |
SFE95765.1 | SFD64669.1 | SAMN02745121_06257 | SAMN02745121_00892 | Hypothetical protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.714 |
SFE95765.1 | SFE95747.1 | SAMN02745121_06257 | SAMN02745121_06256 | Hypothetical protein. | Hypothetical protein. | 0.773 |
SFE95765.1 | SFF00728.1 | SAMN02745121_06257 | SAMN02745121_06470 | Hypothetical protein. | Nicotinamide-nucleotide amidase; Belongs to the CinA family. | 0.688 |
SFE95765.1 | SFF17364.1 | SAMN02745121_06257 | SAMN02745121_07323 | Hypothetical protein. | Amino acid adenylation domain-containing protein. | 0.466 |
SFE95765.1 | SFF19357.1 | SAMN02745121_06257 | SAMN02745121_07429 | Hypothetical protein. | Amino acid adenylation domain-containing protein. | 0.466 |
SFE95765.1 | SFF19374.1 | SAMN02745121_06257 | SAMN02745121_07430 | Hypothetical protein. | Amino acid adenylation domain-containing protein. | 0.466 |
SFE95765.1 | SFF36086.1 | SAMN02745121_06257 | SAMN02745121_08376 | Hypothetical protein. | Amino acid adenylation domain-containing protein. | 0.471 |
SFE95765.1 | SFF50914.1 | SAMN02745121_06257 | SAMN02745121_09234 | Hypothetical protein. | Phosphopantetheine attachment site. | 0.459 |
SFE95765.1 | guaA | SAMN02745121_06257 | SAMN02745121_00654 | Hypothetical protein. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.701 |
SFE95765.1 | guaB | SAMN02745121_06257 | SAMN02745121_00655 | Hypothetical protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.608 |