STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recA-2RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (407 aa)    
Predicted Functional Partners:
SFE06896.1
ATP-dependent DNA helicase, RecQ family/DNA topoisomerase III.
  
 0.996
SFF02820.1
5'-3' exonuclease.
 
 0.973
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.954
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
 
 0.954
polA-2
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.954
SFF34965.1
DNA methylase.
  
 
 0.912
SFE60484.1
ATP-dependent DNA helicase RecQ.
  
 0.836
SFE25505.1
ATP-dependent DNA helicase RecQ.
  
 0.805
SFF47176.1
Flp pilus assembly protein TadD, contains TPR repeats.
  
 
 0.761
SFD54036.1
Recombination protein RecA.
     
 0.756
Your Current Organism:
Nannocystis exedens
NCBI taxonomy Id: 54
Other names: ATCC 25963, DSM 71, N. exedens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.