STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvE_1Branched-chain-amino-acid transaminase; KEGG: cno:NT01CX_0183 5.0e-95 ilvE; branched-chain amino acid aminotransferase; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 7.50. (307 aa)    
Predicted Functional Partners:
thrC_5
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
  
 
 0.664
sulD
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.647
pabB
KEGG: ava:Ava_3468 3.2e-148 anthranilate synthase, component II K13950; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.629
hom_2
KEGG: fma:FMG_0319 2.7e-158 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.611
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.514
tdcB_2
KEGG: apr:Apre_1062 8.6e-107 threonine dehydratase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.439
tdcB_1
Pyridoxal-phosphate dependent protein; KEGG: hbu:Hbut_0216 8.4e-61 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.439
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.438
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.408
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
  
 0.405
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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