Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
benMLysR substrate binding domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the LysR transcriptional regulatory family. (219 aa)    
Predicted Functional Partners:
KXA31757.1
Copper amine oxidase domain protein; KEGG: dca:Desca_1893 1.1e-10 cell wall hydrolase/autolysin; K01448 N-acetylmuramoyl-L-alanine amidase.
 
     0.547
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.480
KXA31896.1
Cyclic nucleotide-binding domain protein; KEGG: fma:FMG_1494 0.00029 pyruvate-formate-lyase-activating enzyme; K04069 pyruvate formate lyase activating enzyme; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.460
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.436
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.423
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.422
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.405
KXA31758.1
Hypothetical protein; KEGG: dme:Dmel_CG18255 1.1e-13 Strn-Mlck; Stretchin-Mlck K00907.
     
 0.401
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
Server load: low (10%) [HD]