close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (325 aa)    
Predicted Functional Partners:
thrA
Aspartate kinase; KEGG: fma:FMG_0317 1.9e-196 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family.
 
 
 0.996
hom_2
KEGG: fma:FMG_0319 2.7e-158 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
 
 0.963
thrC_5
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
  
 
 0.953
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
  
 0.851
KXA31193.1
Hypothetical protein; KEGG: sud:ST398NM01_2520 1.0e-06 Diaminopimelate epimerase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.730
pgk
KEGG: apr:Apre_0766 1.3e-117 phosphoglycerate kinase K00927; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.608
lysS
lysine--tRNA ligase; KEGG: fma:FMG_0987 2.5e-251 lysyl-tRNA synthetase class II; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.595
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.553
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.523
ilvE_1
Branched-chain-amino-acid transaminase; KEGG: cno:NT01CX_0183 5.0e-95 ilvE; branched-chain amino acid aminotransferase; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.514
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
Server load: low (36%) [HD]