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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hom_2KEGG: fma:FMG_0319 2.7e-158 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50. (388 aa)    
Predicted Functional Partners:
thrC_5
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
 
 0.997
thrA
Aspartate kinase; KEGG: fma:FMG_0317 1.9e-196 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family.
 
 0.989
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.963
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 0.887
msrAB
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.683
ilvE_1
Branched-chain-amino-acid transaminase; KEGG: cno:NT01CX_0183 5.0e-95 ilvE; branched-chain amino acid aminotransferase; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.611
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.596
serA
KEGG: apo:Arcpr_0691 1.5e-54 D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.592
pabC
KEGG: ccb:Clocel_0368 1.2e-45 class IV aminotransferase; K02619 4-amino-4-deoxychorismate lyase; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.545
KXA28704.1
KEGG: edi:EDI_341030 7.8e-11 intracellular protein transport protein USO1; Psort location: Cellwall, score: 10.00.
 
     0.525
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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