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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hslOChaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. (306 aa)    
Predicted Functional Partners:
KXA31696.1
Methyltransferase domain protein; KEGG: bmq:BMQ_4579 6.1e-35 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
 
     0.825
cobB
Putative NAD-dependent deacetylase; KEGG: ttm:Tthe_1994 1.2e-70 silent information regulator protein Sir2; K12410 NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 7.50.
       0.793
hpt_1
KEGG: ccb:Clocel_2100 3.0e-49 hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.782
KXA31698.1
KEGG: bst:GYO_0743 1.1e-07 caax amino protease family K07052; Psort location: CytoplasmicMembrane, score: 10.00.
       0.781
KXA31189.1
S4 domain protein; KEGG: hiq:CGSHiGG_06085 6.6e-06 glucose-6-phosphate 1-dehydrogenase K04762; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.706
lon1
Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
  
 0.604
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
   
  
 0.568
KXA31700.1
Hypothetical protein.
       0.549
KXA31694.1
Fic family protein; Psort location: Cytoplasmic, score: 7.50.
       0.542
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
  
  
 0.523
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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