Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gcvTKEGG: elm:ELI_0269 9.9e-90 putative glycine cleavage system T protein; K00605 aminomethyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the GcvT family. (336 aa)    
Predicted Functional Partners:
folD
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.959
purH
KEGG: tmt:Tmath_0637 1.1e-138 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.941
fhs_3
KEGG: faa:HMPREF0389_01605 1.2e-205 formate--tetrahydrofolate ligase; K01938 formate--tetrahydrofolate ligase; Psort location: Cytoplasmic, score: 7.50.
  
 0.940
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 
 0.935
fchA_3
Putative methenyltetrahydrofolate cyclohydrolase; KEGG: ctc:CTC02303 2.7e-48 formiminotetrahydrofolate cyclodeaminase K01746; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.920
folA
KEGG: pce:PECL_916 1.1e-21 dfrA; dihydrofolate reductase; K00287 dihydrofolate reductase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.918
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
     
 0.912
KXA27790.1
KEGG: ctc:CTC02305 2.2e-101 glutamate formiminotransferase K00603; Psort location: Cytoplasmic, score: 7.50.
    
  0.903
gltD
Glutamate synthase; KEGG: clj:CLJU_c37240 2.7e-261 glutamate synthase K00266; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.834
KXA31597.1
KEGG: faa:HMPREF0389_01649 4.9e-159 NAD-specific glutamate dehydrogenase; K00260 glutamate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.827
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.