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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sipTKEGG: cex:CSE_06110 2.9e-28 signal peptidase I K03100; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the peptidase S26 family. (171 aa)    
Predicted Functional Partners:
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
  
 0.602
trmL
RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.551
KXA31591.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: gox:GOX1630 2.6e-59 oxidoreductase K00100; Psort location: Cytoplasmic, score: 7.50.
       0.551
KXA31589.1
DEAD2 domain protein; KEGG: cno:NT01CX_0936 6.3e-175 hypothetical protein; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 7.50.
  
    0.528
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
  
    0.469
phoU
Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.457
KXA31588.1
KEGG: bmq:BMQ_3109 9.7e-05 CAAX amino terminal protease family protein K07052; Psort location: CytoplasmicMembrane, score: 10.00.
       0.434
yvyD
Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
    0.434
tpx
Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
    0.428
KXA28536.1
Hypothetical protein; KEGG: ccb:Clocel_1853 2.5e-05 multi-sensor signal transduction histidine kinase; K07636 two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Psort location: CytoplasmicMembrane, score: 10.00.
   
    0.428
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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