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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folAKEGG: pce:PECL_916 1.1e-21 dfrA; dihydrofolate reductase; K00287 dihydrofolate reductase; Psort location: Cytoplasmic, score: 7.50. (158 aa)    
Predicted Functional Partners:
arlR_2
Putative transcriptional activator protein IrlR; KEGG: cnc:CNE_2c16400 2.0e-36 czcS; sensor protein CzcS K07665; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.789
cusS_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: rrs:RoseRS_2626 1.9e-38 integral membrane sensor signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.784
fgs_1
Protein FolC; KEGG: csc:Csac_2037 5.5e-73 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 7.50.
    
 0.569
fgs_2
Protein FolC; KEGG: apr:Apre_1051 4.8e-90 bifunctional folylpolyglutamate synthase/dihydrofolate synthase; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 7.50.
    
 0.569
KXA31596.1
Glyoxalase family protein; KEGG: cby:CLM_0738 2.8e-07 lactoylglutathione lyase; K01759 lactoylglutathione lyase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.557
sulD
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.554
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.550
msrAB
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.528
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.480
tpiA_3
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.478
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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