| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| eno_5 | fda | HMPREF3229_00344 | HMPREF3229_00271 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | 0.930 |
| eno_5 | gap | HMPREF3229_00344 | HMPREF3229_00602 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: fma:FMG_0793 7.2e-103 glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | 0.976 |
| eno_5 | gpmI_7 | HMPREF3229_00344 | HMPREF3229_00343 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.991 |
| eno_5 | pgk | HMPREF3229_00344 | HMPREF3229_00341 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | KEGG: apr:Apre_0766 1.3e-117 phosphoglycerate kinase K00927; Psort location: Cytoplasmic, score: 9.97. | 0.994 |
| eno_5 | ppsA | HMPREF3229_00344 | HMPREF3229_01200 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.934 |
| eno_5 | pyk | HMPREF3229_00344 | HMPREF3229_00289 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate kinase; KEGG: csc:Csac_1831 1.4e-163 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50. | 0.997 |
| eno_5 | rplD | HMPREF3229_00344 | HMPREF3229_01733 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.925 |
| eno_5 | tal | HMPREF3229_00344 | HMPREF3229_01128 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.916 |
| eno_5 | tkt | HMPREF3229_00344 | HMPREF3229_00619 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.954 |
| eno_5 | tpiA_3 | HMPREF3229_00344 | HMPREF3229_00342 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.987 |
| fda | eno_5 | HMPREF3229_00271 | HMPREF3229_00344 | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.930 |
| fda | gap | HMPREF3229_00271 | HMPREF3229_00602 | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: fma:FMG_0793 7.2e-103 glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | 0.979 |
| fda | gpmI_7 | HMPREF3229_00271 | HMPREF3229_00343 | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.824 |
| fda | pgk | HMPREF3229_00271 | HMPREF3229_00341 | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | KEGG: apr:Apre_0766 1.3e-117 phosphoglycerate kinase K00927; Psort location: Cytoplasmic, score: 9.97. | 0.489 |
| fda | ppsA | HMPREF3229_00271 | HMPREF3229_01200 | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.800 |
| fda | pyk | HMPREF3229_00271 | HMPREF3229_00289 | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | Pyruvate kinase; KEGG: csc:Csac_1831 1.4e-163 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50. | 0.896 |
| fda | tal | HMPREF3229_00271 | HMPREF3229_01128 | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.934 |
| fda | tkt | HMPREF3229_00271 | HMPREF3229_00619 | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.931 |
| fda | tpiA_3 | HMPREF3229_00271 | HMPREF3229_00342 | KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.954 |
| gap | eno_5 | HMPREF3229_00602 | HMPREF3229_00344 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: fma:FMG_0793 7.2e-103 glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.976 |
