Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KXA31449.1Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (170 aa)    
Predicted Functional Partners:
KXA31450.1
ATP:guanido phosphotransferase, catalytic domain protein; KEGG: aar:Acear_0130 3.2e-36 ATP:guanido phosphotransferase; K00936; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.999
ctsR
Putative transcriptional regulator CtsR; Belongs to the CtsR family.
 
  
 0.984
clpC
KEGG: cbb:CLD_0992 1.8e-223 clpC; negative regulator of genetic competence MecB/ClpC K03696; Psort location: Cytoplasmic, score: 9.95; Belongs to the ClpA/ClpB family.
 
  
 0.947
radA
Putative DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
    0.872
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
  
 0.698
KXA30412.1
PIN domain protein; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.534
spoVG
Stage V sporulation protein G; Could be involved in septation.
  
     0.520
KXA31833.1
Hypothetical protein; Belongs to the UPF0297 family.
  
     0.419
KXA28955.1
Endopeptidase Clp; KEGG: bcr:BCAH187_A4003 1.6e-43 Clp protease.
   
  
 0.410
clpP
ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.410
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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