Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cfiBPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1173 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; KEGG: csc:Csac_1831 1.4e-163 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50.
  
 0.964
porA
KEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50.
    
 0.955
ldh
KEGG: aur:HMPREF9243_0952 1.8e-60 L-lactate dehydrogenase K00016; Psort location: Cytoplasmic, score: 9.97; Belongs to the LDH/MDH superfamily.
  
 0.944
KXA30812.1
KEGG: crn:CAR_c13520 1.1e-154 oadA; oxaloacetate decarboxylase subunit alpha K01571; Psort location: Cytoplasmic, score: 7.50.
 
  
0.930
ppsA
Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.929
KXA28721.1
Putative glycolate oxidase, subunit GlcD; KEGG: apr:Apre_1357 8.9e-192 D-lactate dehydrogenase K00104; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.923
KXA31794.1
Biotin-dependent carboxylase domain protein; KEGG: fnu:FN0436 8.8e-82 urea carboxylase; Psort location: Cytoplasmic, score: 7.50.
    
 0.918
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 
 0.909
gcdB
glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
    
  0.907
KXA29688.1
KEGG: lgr:LCGT_0523 1.6e-64 acetyl-CoA carboxylase carboxyl transferase subunit alpha; K01962 acetyl-CoA carboxylase carboxyl transferase subunit alpha; Psort location: Cytoplasmic, score: 9.97.
 
 0.895
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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