| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA28921.1 | dnaN | HMPREF3229_01553 | HMPREF3229_00723 | BRCA1 protein; KEGG: sri:SELR_11040 5.1e-70 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.826 |
| KXA28921.1 | pcrA | HMPREF3229_01553 | HMPREF3229_01193 | BRCA1 protein; KEGG: sri:SELR_11040 5.1e-70 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | Putative ATP-dependent DNA helicase PcrA; KEGG: apr:Apre_0982 2.6e-176 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | 0.515 |
| KXA28921.1 | polA | HMPREF3229_01553 | HMPREF3229_00450 | BRCA1 protein; KEGG: sri:SELR_11040 5.1e-70 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.626 |
| KXA28921.1 | recD | HMPREF3229_01553 | HMPREF3229_00476 | BRCA1 protein; KEGG: sri:SELR_11040 5.1e-70 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.580 |
| KXA31361.1 | KXA31363.1 | HMPREF3229_00475 | HMPREF3229_00477 | PspC domain protein; KEGG: aai:AARI_23710 0.00023 signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.55. | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | 0.536 |
| KXA31361.1 | cfiB | HMPREF3229_00475 | HMPREF3229_00474 | PspC domain protein; KEGG: aai:AARI_23710 0.00023 signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.55. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.609 |
| KXA31361.1 | recD | HMPREF3229_00475 | HMPREF3229_00476 | PspC domain protein; KEGG: aai:AARI_23710 0.00023 signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.55. | Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.527 |
| KXA31363.1 | KXA31361.1 | HMPREF3229_00477 | HMPREF3229_00475 | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | PspC domain protein; KEGG: aai:AARI_23710 0.00023 signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.55. | 0.536 |
| KXA31363.1 | cfiB | HMPREF3229_00477 | HMPREF3229_00474 | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.414 |
| KXA31363.1 | recA | HMPREF3229_00477 | HMPREF3229_01159 | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.442 |
| KXA31363.1 | recD | HMPREF3229_00477 | HMPREF3229_00476 | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.820 |
| addA | pcrA | HMPREF3229_00872 | HMPREF3229_01193 | UvrD/REP helicase; ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | Putative ATP-dependent DNA helicase PcrA; KEGG: apr:Apre_0982 2.6e-176 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | 0.477 |
| addA | polA | HMPREF3229_00872 | HMPREF3229_00450 | UvrD/REP helicase; ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.586 |
| addA | recA | HMPREF3229_00872 | HMPREF3229_01159 | UvrD/REP helicase; ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.479 |
| addA | recD | HMPREF3229_00872 | HMPREF3229_00476 | UvrD/REP helicase; ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.677 |
| cfiB | KXA31361.1 | HMPREF3229_00474 | HMPREF3229_00475 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PspC domain protein; KEGG: aai:AARI_23710 0.00023 signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.55. | 0.609 |
| cfiB | KXA31363.1 | HMPREF3229_00474 | HMPREF3229_00477 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | 0.414 |
| cfiB | recD | HMPREF3229_00474 | HMPREF3229_00476 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.429 |
| dnaN | KXA28921.1 | HMPREF3229_00723 | HMPREF3229_01553 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | BRCA1 protein; KEGG: sri:SELR_11040 5.1e-70 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | 0.826 |
| dnaN | pcrA | HMPREF3229_00723 | HMPREF3229_01193 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative ATP-dependent DNA helicase PcrA; KEGG: apr:Apre_0982 2.6e-176 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | 0.871 |
