STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpxRedoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (166 aa)    
Predicted Functional Partners:
rlmH
rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.782
msrAB
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.645
KXA30950.1
Hypothetical protein; KEGG: mae:Maeo_0964 0.0014 DsrE family protein; K07235 tRNA 2-thiouridine synthesizing protein D.
       0.551
KXA29449.1
Transcriptional regulator, MarR family; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.487
KXA28663.1
Transcriptional regulator MntR family protein; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.487
sipS
KEGG: apr:Apre_1183 1.7e-30 signal peptidase I; K03100 signal peptidase I; Psort location: Cellwall, score: 8.75; Belongs to the peptidase S26 family.
  
    0.461
sipT
KEGG: cex:CSE_06110 2.9e-28 signal peptidase I K03100; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the peptidase S26 family.
   
    0.456
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.440
trxB_1
KEGG: thx:Thet_1993 1.4e-92 thioredoxin reductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 9.97.
  
  
 0.439
trxB_2
KEGG: dai:Desaci_3389 3.6e-76 thioredoxin-disulfide reductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 9.97.
  
  
 0.439
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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