| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA27840.1 | rlmH | HMPREF3229_01911 | HMPREF3229_00547 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.450 |
| KXA30950.1 | rlmH | HMPREF3229_00548 | HMPREF3229_00547 | Hypothetical protein; KEGG: mae:Maeo_0964 0.0014 DsrE family protein; K07235 tRNA 2-thiouridine synthesizing protein D. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.551 |
| KXA30950.1 | tpx | HMPREF3229_00548 | HMPREF3229_00546 | Hypothetical protein; KEGG: mae:Maeo_0964 0.0014 DsrE family protein; K07235 tRNA 2-thiouridine synthesizing protein D. | Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.551 |
| dacA-2 | rlmH | HMPREF3229_00739 | HMPREF3229_00547 | KEGG: apr:Apre_1285 2.3e-51 serine-type D-Ala-D-Ala carboxypeptidase K07258; Psort location: CytoplasmicMembrane, score: 8.78; Belongs to the peptidase S11 family. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.461 |
| nadD | rlmH | HMPREF3229_00112 | HMPREF3229_00547 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.568 |
| nadD | ybeB | HMPREF3229_00112 | HMPREF3229_00115 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.988 |
| polA | rlmH | HMPREF3229_00450 | HMPREF3229_00547 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.500 |
| polA | rsmB | HMPREF3229_00450 | HMPREF3229_00953 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.506 |
| polA | ybeB | HMPREF3229_00450 | HMPREF3229_00115 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.547 |
| rlmH | KXA27840.1 | HMPREF3229_00547 | HMPREF3229_01911 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.450 |
| rlmH | KXA30950.1 | HMPREF3229_00547 | HMPREF3229_00548 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Hypothetical protein; KEGG: mae:Maeo_0964 0.0014 DsrE family protein; K07235 tRNA 2-thiouridine synthesizing protein D. | 0.551 |
| rlmH | dacA-2 | HMPREF3229_00547 | HMPREF3229_00739 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | KEGG: apr:Apre_1285 2.3e-51 serine-type D-Ala-D-Ala carboxypeptidase K07258; Psort location: CytoplasmicMembrane, score: 8.78; Belongs to the peptidase S11 family. | 0.461 |
| rlmH | nadD | HMPREF3229_00547 | HMPREF3229_00112 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.568 |
| rlmH | polA | HMPREF3229_00547 | HMPREF3229_00450 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.500 |
| rlmH | rsmB | HMPREF3229_00547 | HMPREF3229_00953 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.459 |
| rlmH | rsmD | HMPREF3229_00547 | HMPREF3229_00446 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | RNA methyltransferase, RsmD family; KEGG: lmy:LM5923_2205 1.0e-30 hypothetical protein; K08316 16S rRNA (guanine966-N2)-methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.462 |
| rlmH | rsmI | HMPREF3229_00547 | HMPREF3229_01118 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.439 |
| rlmH | tpx | HMPREF3229_00547 | HMPREF3229_00546 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.782 |
| rlmH | ybeB | HMPREF3229_00547 | HMPREF3229_00115 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.726 |
| rsmB | polA | HMPREF3229_00953 | HMPREF3229_00450 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.506 |