| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bigR_1 | copA | HMPREF3229_00662 | HMPREF3229_00699 | Putative arsenical resistance operon repressor; KEGG: xca:xccb100_2759 1.8e-07 methyltransferase K03892; Psort location: Cytoplasmic, score: 7.50. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.538 |
| bigR_1 | porA | HMPREF3229_00662 | HMPREF3229_00890 | Putative arsenical resistance operon repressor; KEGG: xca:xccb100_2759 1.8e-07 methyltransferase K03892; Psort location: Cytoplasmic, score: 7.50. | KEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50. | 0.449 |
| bigR_1 | ziaR | HMPREF3229_00662 | HMPREF3229_00575 | Putative arsenical resistance operon repressor; KEGG: xca:xccb100_2759 1.8e-07 methyltransferase K03892; Psort location: Cytoplasmic, score: 7.50. | Transcriptional repressor SmtB family protein; KEGG: rru:Rru_A1450 7.6e-08 ArsR family transcriptional regulator K03741; Psort location: Cytoplasmic, score: 7.50. | 0.593 |
| cadA | copA | HMPREF3229_00409 | HMPREF3229_00699 | Cadmium-exporting ATPase; KEGG: fpe:Ferpe_0668 3.8e-149 heavy metal-translocating P-type ATPase; K01534 Cd2+/Zn2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.896 |
| cadA | porA | HMPREF3229_00409 | HMPREF3229_00890 | Cadmium-exporting ATPase; KEGG: fpe:Ferpe_0668 3.8e-149 heavy metal-translocating P-type ATPase; K01534 Cd2+/Zn2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50. | 0.531 |
| cadA | ziaR | HMPREF3229_00409 | HMPREF3229_00575 | Cadmium-exporting ATPase; KEGG: fpe:Ferpe_0668 3.8e-149 heavy metal-translocating P-type ATPase; K01534 Cd2+/Zn2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00. | Transcriptional repressor SmtB family protein; KEGG: rru:Rru_A1450 7.6e-08 ArsR family transcriptional regulator K03741; Psort location: Cytoplasmic, score: 7.50. | 0.834 |
| copA | bigR_1 | HMPREF3229_00699 | HMPREF3229_00662 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Putative arsenical resistance operon repressor; KEGG: xca:xccb100_2759 1.8e-07 methyltransferase K03892; Psort location: Cytoplasmic, score: 7.50. | 0.538 |
| copA | cadA | HMPREF3229_00699 | HMPREF3229_00409 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Cadmium-exporting ATPase; KEGG: fpe:Ferpe_0668 3.8e-149 heavy metal-translocating P-type ATPase; K01534 Cd2+/Zn2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.896 |
| copA | nrdH | HMPREF3229_00699 | HMPREF3229_00574 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50. | 0.523 |
| copA | porA | HMPREF3229_00699 | HMPREF3229_00890 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50. | 0.542 |
| copA | ziaR | HMPREF3229_00699 | HMPREF3229_00575 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Transcriptional repressor SmtB family protein; KEGG: rru:Rru_A1450 7.6e-08 ArsR family transcriptional regulator K03741; Psort location: Cytoplasmic, score: 7.50. | 0.632 |
| copA | zosA | HMPREF3229_00699 | HMPREF3229_00230 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Heavy metal translocating P-type ATPase; KEGG: mru:mru_0534 4.5e-149 ATPase; Psort location: CytoplasmicMembrane, score: 8.78. | 0.901 |
| metG_1 | nrdH | HMPREF3229_00579 | HMPREF3229_00574 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50. | 0.448 |
| metG_1 | rnmV | HMPREF3229_00579 | HMPREF3229_00577 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. | 0.822 |
| metG_1 | rsmA | HMPREF3229_00579 | HMPREF3229_00576 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | KEGG: bbe:BBR47_00900 5.3e-52 ksgA; dimethyladenosine transferase K02528; Psort location: Cytoplasmic, score: 9.97; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | 0.724 |
| metG_1 | ycfH | HMPREF3229_00579 | HMPREF3229_00578 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Hydrolase, TatD family; KEGG: faa:HMPREF0389_00352 3.5e-71 TatD family hydrolase; K03424 TatD DNase family protein; Psort location: Cytoplasmic, score: 9.97. | 0.917 |
| metG_1 | ziaR | HMPREF3229_00579 | HMPREF3229_00575 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Transcriptional repressor SmtB family protein; KEGG: rru:Rru_A1450 7.6e-08 ArsR family transcriptional regulator K03741; Psort location: Cytoplasmic, score: 7.50. | 0.579 |
| nrdH | copA | HMPREF3229_00574 | HMPREF3229_00699 | Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.523 |
| nrdH | metG_1 | HMPREF3229_00574 | HMPREF3229_00579 | Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.448 |
| nrdH | rnmV | HMPREF3229_00574 | HMPREF3229_00577 | Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50. | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. | 0.520 |