Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (254 aa)    
Predicted Functional Partners:
KXA29558.1
Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
 0.902
yajL
DJ-1 family protein; KEGG: scp:HMPREF0833_10842 4.7e-28 rimI; ribosomal-protein-alanine acetyltransferase K03152; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.810
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.768
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.743
KXA31039.1
KEGG: shn:Shewana3_3300 7.7e-10 chromate transporter K07240; Psort location: CytoplasmicMembrane, score: 10.00.
       0.552
KXA31040.1
KEGG: apb:SAR116_1094 9.3e-14 chromate transporter K07240; Psort location: CytoplasmicMembrane, score: 10.00.
       0.552
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.543
purL
KEGG: apr:Apre_1107 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.97.
     
 0.519
thrC_5
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
  
  
 0.513
fieF
Cation diffusion facilitator family transporter; KEGG: bqy:MUS_3253 6.1e-35 cation efflux system protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
    0.503
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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