Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tadACytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (150 aa)    
Predicted Functional Partners:
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
 
 
 0.820
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.809
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 0.800
exoA_2
Exodeoxyribonuclease III; KEGG: aur:HMPREF9243_1834 1.7e-108 xth; exodeoxyribonuclease III K01142; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.721
KXA30763.1
KEGG: cbn:CbC4_0917 1.8e-49 3-methyladenine DNA glycosylase; K03652 DNA-3-methyladenine glycosylase; Psort location: Cytoplasmic, score: 7.50; Belongs to the DNA glycosylase MPG family.
 
  
 0.720
gloA
Putative lactoylglutathione lyase; KEGG: apr:Apre_0364 2.5e-45 Glyoxalase/bleomycin resistance protein/dioxygenase; K01759 lactoylglutathione lyase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.627
rsmI
S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
  
 0.604
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.575
ydiC
Universal bacterial protein YeaZ; KEGG: snc:HMPREF0837_10435 1.8e-28 gcp; M22 family O-sialoglycoprotein endopeptidase.
 
  
 0.573
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.556
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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