| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA30413.1 | copA | HMPREF3229_00876 | HMPREF3229_00699 | Hypothetical protein; KEGG: sta:STHERM_c18850 2.4e-15 DNA protection during starvation protein K04047; Psort location: Cytoplasmic, score: 9.97. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.694 |
| KXA30413.1 | msrAB | HMPREF3229_00876 | HMPREF3229_00757 | Hypothetical protein; KEGG: sta:STHERM_c18850 2.4e-15 DNA protection during starvation protein K04047; Psort location: Cytoplasmic, score: 9.97. | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.493 |
| KXA30917.1 | copA | HMPREF3229_00697 | HMPREF3229_00699 | Hypothetical protein. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.773 |
| KXA30917.1 | csoR | HMPREF3229_00697 | HMPREF3229_00698 | Hypothetical protein. | Copper-sensing transcriptional repressor CsoR family protein; Psort location: Cytoplasmic, score: 7.50. | 0.773 |
| KXA31090.1 | copA | HMPREF3229_00530 | HMPREF3229_00699 | Transcriptional regulator, BlaI/MecI/CopY family; KEGG: bcz:BCZK0993 6.6e-06 blaI; beta-lactamase K07737; Psort location: Cytoplasmic, score: 7.50. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.809 |
| cadA | copA | HMPREF3229_00409 | HMPREF3229_00699 | Cadmium-exporting ATPase; KEGG: fpe:Ferpe_0668 3.8e-149 heavy metal-translocating P-type ATPase; K01534 Cd2+/Zn2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.896 |
| cadA | ziaR | HMPREF3229_00409 | HMPREF3229_00575 | Cadmium-exporting ATPase; KEGG: fpe:Ferpe_0668 3.8e-149 heavy metal-translocating P-type ATPase; K01534 Cd2+/Zn2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00. | Transcriptional repressor SmtB family protein; KEGG: rru:Rru_A1450 7.6e-08 ArsR family transcriptional regulator K03741; Psort location: Cytoplasmic, score: 7.50. | 0.834 |
| copA | KXA30413.1 | HMPREF3229_00699 | HMPREF3229_00876 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Hypothetical protein; KEGG: sta:STHERM_c18850 2.4e-15 DNA protection during starvation protein K04047; Psort location: Cytoplasmic, score: 9.97. | 0.694 |
| copA | KXA30917.1 | HMPREF3229_00699 | HMPREF3229_00697 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Hypothetical protein. | 0.773 |
| copA | KXA31090.1 | HMPREF3229_00699 | HMPREF3229_00530 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Transcriptional regulator, BlaI/MecI/CopY family; KEGG: bcz:BCZK0993 6.6e-06 blaI; beta-lactamase K07737; Psort location: Cytoplasmic, score: 7.50. | 0.809 |
| copA | cadA | HMPREF3229_00699 | HMPREF3229_00409 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Cadmium-exporting ATPase; KEGG: fpe:Ferpe_0668 3.8e-149 heavy metal-translocating P-type ATPase; K01534 Cd2+/Zn2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.896 |
| copA | csoR | HMPREF3229_00699 | HMPREF3229_00698 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Copper-sensing transcriptional repressor CsoR family protein; Psort location: Cytoplasmic, score: 7.50. | 0.954 |
| copA | cueR | HMPREF3229_00699 | HMPREF3229_01806 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | 0.625 |
| copA | fieF | HMPREF3229_00699 | HMPREF3229_00634 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Cation diffusion facilitator family transporter; KEGG: bqy:MUS_3253 6.1e-35 cation efflux system protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.641 |
| copA | msrAB | HMPREF3229_00699 | HMPREF3229_00757 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.643 |
| copA | ziaR | HMPREF3229_00699 | HMPREF3229_00575 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Transcriptional repressor SmtB family protein; KEGG: rru:Rru_A1450 7.6e-08 ArsR family transcriptional regulator K03741; Psort location: Cytoplasmic, score: 7.50. | 0.632 |
| copA | zosA | HMPREF3229_00699 | HMPREF3229_00230 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Heavy metal translocating P-type ATPase; KEGG: mru:mru_0534 4.5e-149 ATPase; Psort location: CytoplasmicMembrane, score: 8.78. | 0.901 |
| csoR | KXA30917.1 | HMPREF3229_00698 | HMPREF3229_00697 | Copper-sensing transcriptional repressor CsoR family protein; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein. | 0.773 |
| csoR | copA | HMPREF3229_00698 | HMPREF3229_00699 | Copper-sensing transcriptional repressor CsoR family protein; Psort location: Cytoplasmic, score: 7.50. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.954 |
| cueR | copA | HMPREF3229_01806 | HMPREF3229_00699 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.625 |