| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA29647.1 | dnaE | HMPREF3229_01272 | HMPREF3229_00291 | KEGG: amt:Amet_3057 1.3e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta. | KEGG: txy:Thexy_0632 0. DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97. | 0.990 |
| KXA29647.1 | dnaN | HMPREF3229_01272 | HMPREF3229_00723 | KEGG: amt:Amet_3057 1.3e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.991 |
| KXA29647.1 | dnaX_1 | HMPREF3229_01272 | HMPREF3229_01810 | KEGG: amt:Amet_3057 1.3e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta. | Hypothetical protein; KEGG: aoe:Clos_0062 1.8e-42 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | 0.989 |
| KXA29647.1 | mutL | HMPREF3229_01272 | HMPREF3229_01174 | KEGG: amt:Amet_3057 1.3e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.403 |
| KXA29647.1 | polA | HMPREF3229_01272 | HMPREF3229_00450 | KEGG: amt:Amet_3057 1.3e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.639 |
| KXA31589.1 | dnaN | HMPREF3229_00311 | HMPREF3229_00723 | DEAD2 domain protein; KEGG: cno:NT01CX_0936 6.3e-175 hypothetical protein; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 7.50. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.944 |
| KXA31589.1 | mutL | HMPREF3229_00311 | HMPREF3229_01174 | DEAD2 domain protein; KEGG: cno:NT01CX_0936 6.3e-175 hypothetical protein; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 7.50. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.452 |
| KXA31589.1 | polA | HMPREF3229_00311 | HMPREF3229_00450 | DEAD2 domain protein; KEGG: cno:NT01CX_0936 6.3e-175 hypothetical protein; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 7.50. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.964 |
| dnaA | dnaN | HMPREF3229_00724 | HMPREF3229_00723 | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.992 |
| dnaA | polA | HMPREF3229_00724 | HMPREF3229_00450 | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.531 |
| dnaA | recF | HMPREF3229_00724 | HMPREF3229_00721 | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.904 |
| dnaE | KXA29647.1 | HMPREF3229_00291 | HMPREF3229_01272 | KEGG: txy:Thexy_0632 0. DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97. | KEGG: amt:Amet_3057 1.3e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta. | 0.990 |
| dnaE | dnaN | HMPREF3229_00291 | HMPREF3229_00723 | KEGG: txy:Thexy_0632 0. DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.989 |
| dnaE | dnaX_1 | HMPREF3229_00291 | HMPREF3229_01810 | KEGG: txy:Thexy_0632 0. DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; KEGG: aoe:Clos_0062 1.8e-42 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | 0.984 |
| dnaE | polA | HMPREF3229_00291 | HMPREF3229_00450 | KEGG: txy:Thexy_0632 0. DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.645 |
| dnaN | KXA29647.1 | HMPREF3229_00723 | HMPREF3229_01272 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: amt:Amet_3057 1.3e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta. | 0.991 |
| dnaN | KXA31589.1 | HMPREF3229_00723 | HMPREF3229_00311 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DEAD2 domain protein; KEGG: cno:NT01CX_0936 6.3e-175 hypothetical protein; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 7.50. | 0.944 |
| dnaN | dnaA | HMPREF3229_00723 | HMPREF3229_00724 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.992 |
| dnaN | dnaE | HMPREF3229_00723 | HMPREF3229_00291 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: txy:Thexy_0632 0. DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97. | 0.989 |
| dnaN | dnaX_1 | HMPREF3229_00723 | HMPREF3229_01810 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; KEGG: aoe:Clos_0062 1.8e-42 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | 0.982 |
