| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA30870.1 | parB | HMPREF3229_00735 | HMPREF3229_00733 | Hypothetical protein. | Putative stage 0 sporulation protein J; KEGG: pub:SAR11_0354 1.1e-44 parB; chromosome partitioning protein K03497; Psort location: Cytoplasmic, score: 9.97; Belongs to the ParB family. | 0.775 |
| KXA30870.1 | rsmG | HMPREF3229_00735 | HMPREF3229_00731 | Hypothetical protein. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.416 |
| KXA30870.1 | soj | HMPREF3229_00735 | HMPREF3229_00732 | Hypothetical protein. | KEGG: ccm:Ccan_17350 1.1e-58 Sporulation initiation inhibitor protein soj K03496; Psort location: CytoplasmicMembrane, score: 8.78. | 0.775 |
| KXA30870.1 | yddE | HMPREF3229_00735 | HMPREF3229_00734 | Hypothetical protein. | Phenazine biosynthesis protein, PhzF family; KEGG: nde:NIDE2777 2.7e-23 yddE; isomerase K06998; Psort location: Cytoplasmic, score: 7.50. | 0.775 |
| birA | dnaA | HMPREF3229_01815 | HMPREF3229_00724 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.445 |
| birA | soj | HMPREF3229_01815 | HMPREF3229_00732 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | KEGG: ccm:Ccan_17350 1.1e-58 Sporulation initiation inhibitor protein soj K03496; Psort location: CytoplasmicMembrane, score: 8.78. | 0.539 |
| birA | spoIIIE | HMPREF3229_01815 | HMPREF3229_01155 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 4.0e-109 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | 0.416 |
| dnaA | birA | HMPREF3229_00724 | HMPREF3229_01815 | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.445 |
| dnaA | parB | HMPREF3229_00724 | HMPREF3229_00733 | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Putative stage 0 sporulation protein J; KEGG: pub:SAR11_0354 1.1e-44 parB; chromosome partitioning protein K03497; Psort location: Cytoplasmic, score: 9.97; Belongs to the ParB family. | 0.572 |
| dnaA | rsmG | HMPREF3229_00724 | HMPREF3229_00731 | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.411 |
| dnaA | soj | HMPREF3229_00724 | HMPREF3229_00732 | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | KEGG: ccm:Ccan_17350 1.1e-58 Sporulation initiation inhibitor protein soj K03496; Psort location: CytoplasmicMembrane, score: 8.78. | 0.672 |
| dnaA | spoIIIE | HMPREF3229_00724 | HMPREF3229_01155 | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 4.0e-109 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | 0.546 |
| ffh | ftsZ | HMPREF3229_00898 | HMPREF3229_00939 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.574 |
| ffh | soj | HMPREF3229_00898 | HMPREF3229_00732 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | KEGG: ccm:Ccan_17350 1.1e-58 Sporulation initiation inhibitor protein soj K03496; Psort location: CytoplasmicMembrane, score: 8.78. | 0.602 |
| ftsZ | ffh | HMPREF3229_00939 | HMPREF3229_00898 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.574 |
| ftsZ | ligA_2 | HMPREF3229_00939 | HMPREF3229_01192 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.495 |
| ftsZ | parB | HMPREF3229_00939 | HMPREF3229_00733 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Putative stage 0 sporulation protein J; KEGG: pub:SAR11_0354 1.1e-44 parB; chromosome partitioning protein K03497; Psort location: Cytoplasmic, score: 9.97; Belongs to the ParB family. | 0.642 |
| ftsZ | soj | HMPREF3229_00939 | HMPREF3229_00732 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | KEGG: ccm:Ccan_17350 1.1e-58 Sporulation initiation inhibitor protein soj K03496; Psort location: CytoplasmicMembrane, score: 8.78. | 0.600 |
| ftsZ | spoIIIE | HMPREF3229_00939 | HMPREF3229_01155 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 4.0e-109 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | 0.453 |
| ligA_2 | ftsZ | HMPREF3229_01192 | HMPREF3229_00939 | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.495 |