Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
folEGTP cyclohydrolase I; KEGG: sne:SPN23F_02800 4.0e-70 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50. (184 aa)    
Predicted Functional Partners:
sulD
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 0.999
sulA
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 0.976
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.950
KXA30875.1
HDIG domain protein; KEGG: drt:Dret_2207 0.00065 phosphodiesterase K06950; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.863
nrdD
KEGG: fma:FMG_1178 1.2e-299 anaerobic ribonucleoside triphosphate reductase; K00527 ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 7.50.
    
  0.804
relA
Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.800
KXA29577.1
Putative adenylyl cyclase CyaB; KEGG: apr:Apre_0779 1.1e-28 adenylate cyclase; K05873 adenylate cyclase, class 2; Psort location: Cytoplasmic, score: 7.50.
     
  0.800
ftsH_3
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
 
    0.767
lytG
KEGG: bsr:I33_3196 2.8e-30 Exo-glucosaminidase LytG; Psort location: Extracellular, score: 8.42.
       0.757
KXA30878.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.757
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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