Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nrdARibonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (842 aa)    
Predicted Functional Partners:
nrdB
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 0.999
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.956
grxC
Glutaredoxin; KEGG: eta:ETA_00890 1.1e-05 grxC; glutaredoxin K03676; Psort location: Cytoplasmic, score: 7.50.
  
 0.950
nrdH
Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50.
  
 0.950
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.944
cmk
Cytidylate kinase; KEGG: tte:TTE1350 8.3e-54 cmk; cytidylate kinase; K00945 cytidylate kinase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.938
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.937
trxA
Thioredoxin; KEGG: sis:LS215_0050 2.5e-08 thioredoxin K03671; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.918
gmk_2
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.913
gmk_1
Putative guanylate kinase; KEGG: sul:SYO3AOP1_0874 5.9e-21 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.97.
    
 0.913
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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