| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bsaA | msrAB | HMPREF3229_01355 | HMPREF3229_00757 | KEGG: bpb:bpr_I2927 1.4e-60 glutathione peroxidase K00432; Belongs to the glutathione peroxidase family. | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.807 |
| bsaA | nrdH | HMPREF3229_01355 | HMPREF3229_00574 | KEGG: bpb:bpr_I2927 1.4e-60 glutathione peroxidase K00432; Belongs to the glutathione peroxidase family. | Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50. | 0.459 |
| bsaA | resA_2 | HMPREF3229_01355 | HMPREF3229_01353 | KEGG: bpb:bpr_I2927 1.4e-60 glutathione peroxidase K00432; Belongs to the glutathione peroxidase family. | Redoxin family protein; KEGG: aca:ACP_1678 1.6e-11 thiol-disulfide oxidoreductase. | 0.613 |
| grpE | msrAB | HMPREF3229_01265 | HMPREF3229_00757 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.724 |
| grpE | resA_2 | HMPREF3229_01265 | HMPREF3229_01353 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Redoxin family protein; KEGG: aca:ACP_1678 1.6e-11 thiol-disulfide oxidoreductase. | 0.425 |
| grpE | rplL | HMPREF3229_01265 | HMPREF3229_00302 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.599 |
| grxC | msrAB | HMPREF3229_00259 | HMPREF3229_00757 | Glutaredoxin; KEGG: eta:ETA_00890 1.1e-05 grxC; glutaredoxin K03676; Psort location: Cytoplasmic, score: 7.50. | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.854 |
| msrAB | bsaA | HMPREF3229_00757 | HMPREF3229_01355 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | KEGG: bpb:bpr_I2927 1.4e-60 glutathione peroxidase K00432; Belongs to the glutathione peroxidase family. | 0.807 |
| msrAB | grpE | HMPREF3229_00757 | HMPREF3229_01265 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.724 |
| msrAB | grxC | HMPREF3229_00757 | HMPREF3229_00259 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Glutaredoxin; KEGG: eta:ETA_00890 1.1e-05 grxC; glutaredoxin K03676; Psort location: Cytoplasmic, score: 7.50. | 0.854 |
| msrAB | nrdH | HMPREF3229_00757 | HMPREF3229_00574 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50. | 0.854 |
| msrAB | resA_2 | HMPREF3229_00757 | HMPREF3229_01353 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Redoxin family protein; KEGG: aca:ACP_1678 1.6e-11 thiol-disulfide oxidoreductase. | 0.983 |
| msrAB | rplL | HMPREF3229_00757 | HMPREF3229_00302 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.758 |
| msrAB | rplO | HMPREF3229_00757 | HMPREF3229_01751 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.737 |
| msrAB | rpmB | HMPREF3229_00757 | HMPREF3229_00442 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Ribosomal protein L28; KEGG: apb:SAR116_1905 0.0023 50S ribosomal protein L28 K02902; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL28 family. | 0.755 |
| msrAB | rpmJ | HMPREF3229_00757 | HMPREF3229_01756 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Ribosomal protein L36; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL36 family. | 0.782 |
| msrAB | rpsP | HMPREF3229_00757 | HMPREF3229_00899 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Ribosomal protein S16; KEGG: apb:SAR116_1817 9.2e-16 30S ribosomal protein S16 K02959; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bS16 family. | 0.756 |
| nrdH | bsaA | HMPREF3229_00574 | HMPREF3229_01355 | Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50. | KEGG: bpb:bpr_I2927 1.4e-60 glutathione peroxidase K00432; Belongs to the glutathione peroxidase family. | 0.459 |
| nrdH | msrAB | HMPREF3229_00574 | HMPREF3229_00757 | Hypothetical protein; KEGG: mpl:Mpal_0406 8.3e-07 glutaredoxin; K03387 alkyl hydroperoxide reductase subunit F; Psort location: Cytoplasmic, score: 7.50. | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.854 |
| resA_2 | bsaA | HMPREF3229_01353 | HMPREF3229_01355 | Redoxin family protein; KEGG: aca:ACP_1678 1.6e-11 thiol-disulfide oxidoreductase. | KEGG: bpb:bpr_I2927 1.4e-60 glutathione peroxidase K00432; Belongs to the glutathione peroxidase family. | 0.613 |
