| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| guaA | purC | HMPREF3229_00210 | HMPREF3229_00808 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | KEGG: faa:HMPREF0389_00399 6.9e-66 phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 7.50. | 0.720 |
| guaA | purD | HMPREF3229_00210 | HMPREF3229_00813 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | KEGG: cdc:CD196_0234 3.3e-114 purD; phosphoribosylamine--glycine ligase; K01945 phosphoribosylamine--glycine ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the GARS family. | 0.843 |
| guaA | purE | HMPREF3229_00210 | HMPREF3229_00809 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.588 |
| guaA | purF | HMPREF3229_00210 | HMPREF3229_01478 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.798 |
| guaA | purH | HMPREF3229_00210 | HMPREF3229_00812 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | KEGG: tmt:Tmath_0637 1.1e-138 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 7.50. | 0.849 |
| guaA | purL | HMPREF3229_00210 | HMPREF3229_01479 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | KEGG: apr:Apre_1107 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.97. | 0.986 |
| guaA | purM | HMPREF3229_00210 | HMPREF3229_00810 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | KEGG: awo:Awo_c16370 5.9e-108 purM; phosphoribosylformylglycinamidine cyclo-ligase PurM K01933; Psort location: Cytoplasmic, score: 9.97. | 0.704 |
| guaA | purN | HMPREF3229_00210 | HMPREF3229_00811 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.673 |
| guaA | thrC_5 | HMPREF3229_00210 | HMPREF3229_00221 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate. | 0.589 |
| ppk | purC | HMPREF3229_00807 | HMPREF3229_00808 | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | KEGG: faa:HMPREF0389_00399 6.9e-66 phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 7.50. | 0.415 |
| ppk | purD | HMPREF3229_00807 | HMPREF3229_00813 | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | KEGG: cdc:CD196_0234 3.3e-114 purD; phosphoribosylamine--glycine ligase; K01945 phosphoribosylamine--glycine ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the GARS family. | 0.421 |
| ppk | purE | HMPREF3229_00807 | HMPREF3229_00809 | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.401 |
| ppk | purH | HMPREF3229_00807 | HMPREF3229_00812 | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | KEGG: tmt:Tmath_0637 1.1e-138 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 7.50. | 0.467 |
| ppk | purM | HMPREF3229_00807 | HMPREF3229_00810 | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | KEGG: awo:Awo_c16370 5.9e-108 purM; phosphoribosylformylglycinamidine cyclo-ligase PurM K01933; Psort location: Cytoplasmic, score: 9.97. | 0.662 |
| ppk | purN | HMPREF3229_00807 | HMPREF3229_00811 | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.740 |
| purC | guaA | HMPREF3229_00808 | HMPREF3229_00210 | KEGG: faa:HMPREF0389_00399 6.9e-66 phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 7.50. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.720 |
| purC | ppk | HMPREF3229_00808 | HMPREF3229_00807 | KEGG: faa:HMPREF0389_00399 6.9e-66 phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 7.50. | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.415 |
| purC | purD | HMPREF3229_00808 | HMPREF3229_00813 | KEGG: faa:HMPREF0389_00399 6.9e-66 phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 7.50. | KEGG: cdc:CD196_0234 3.3e-114 purD; phosphoribosylamine--glycine ligase; K01945 phosphoribosylamine--glycine ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the GARS family. | 0.994 |
| purC | purE | HMPREF3229_00808 | HMPREF3229_00809 | KEGG: faa:HMPREF0389_00399 6.9e-66 phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 7.50. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
| purC | purF | HMPREF3229_00808 | HMPREF3229_01478 | KEGG: faa:HMPREF0389_00399 6.9e-66 phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 7.50. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.956 |
