| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA30368.1 | KXA30370.1 | HMPREF3229_00829 | HMPREF3229_00831 | Prepilin-type cleavage/methylation protein. | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | 0.773 |
| KXA30368.1 | KXA30374.1 | HMPREF3229_00829 | HMPREF3229_00835 | Prepilin-type cleavage/methylation protein. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.579 |
| KXA30368.1 | KXA30819.1 | HMPREF3229_00829 | HMPREF3229_00827 | Prepilin-type cleavage/methylation protein. | Hypothetical protein; KEGG: pfe:PSF113_5005 0.0016 pilC; protein PilC K02653. | 0.855 |
| KXA30368.1 | comEA | HMPREF3229_00829 | HMPREF3229_00432 | Prepilin-type cleavage/methylation protein. | comEA protein; KEGG: has:Halsa_0780 1.8e-06 glycogen/starch synthase K00703; Psort location: CytoplasmicMembrane, score: 9.51. | 0.616 |
| KXA30368.1 | epsE | HMPREF3229_00829 | HMPREF3229_00826 | Prepilin-type cleavage/methylation protein. | KEGG: pen:PSEEN2333 5.7e-87 XcpR-2; type II secretion pathway protein E K02454; Psort location: Cytoplasmic, score: 9.97. | 0.915 |
| KXA30368.1 | epsF | HMPREF3229_00829 | HMPREF3229_00828 | Prepilin-type cleavage/methylation protein. | Bacterial type II secretion system protein F domain protein; KEGG: pfe:PSF113_5005 5.4e-27 pilC; protein PilC K02653; Psort location: CytoplasmicMembrane, score: 10.00. | 0.928 |
| KXA30368.1 | hypE | HMPREF3229_00829 | HMPREF3229_00832 | Prepilin-type cleavage/methylation protein. | Hypothetical protein; KEGG: tep:TepRe1_0239 2.7e-55 Thiamine-phosphate kinase; Psort location: Cytoplasmic, score: 7.50. | 0.775 |
| KXA30368.1 | lytC | HMPREF3229_00829 | HMPREF3229_00833 | Prepilin-type cleavage/methylation protein. | KEGG: ccl:Clocl_1228 6.3e-45 N-acetylmuramoyl-L-alanine amidase; K01448 N-acetylmuramoyl-L-alanine amidase; Psort location: Cellwall, score: 8.28. | 0.599 |
| KXA30368.1 | outO | HMPREF3229_00829 | HMPREF3229_00830 | Prepilin-type cleavage/methylation protein. | Bacterial peptidase A24 protein; KEGG: clj:CLJU_c05610 7.7e-35 bifunctional type IV leader peptidase/N-methyltransferase; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.919 |
| KXA30368.1 | smf | HMPREF3229_00829 | HMPREF3229_00824 | Prepilin-type cleavage/methylation protein. | DNA protecting protein DprA; KEGG: ccm:Ccan_01460 1.2e-43 protein smf K04096; Psort location: Cytoplasmic, score: 7.50. | 0.748 |
| KXA30370.1 | KXA30368.1 | HMPREF3229_00831 | HMPREF3229_00829 | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | Prepilin-type cleavage/methylation protein. | 0.773 |
| KXA30370.1 | KXA30374.1 | HMPREF3229_00831 | HMPREF3229_00835 | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.557 |
| KXA30370.1 | KXA30819.1 | HMPREF3229_00831 | HMPREF3229_00827 | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: pfe:PSF113_5005 0.0016 pilC; protein PilC K02653. | 0.517 |
| KXA30370.1 | epsE | HMPREF3229_00831 | HMPREF3229_00826 | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | KEGG: pen:PSEEN2333 5.7e-87 XcpR-2; type II secretion pathway protein E K02454; Psort location: Cytoplasmic, score: 9.97. | 0.517 |
| KXA30370.1 | epsF | HMPREF3229_00831 | HMPREF3229_00828 | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | Bacterial type II secretion system protein F domain protein; KEGG: pfe:PSF113_5005 5.4e-27 pilC; protein PilC K02653; Psort location: CytoplasmicMembrane, score: 10.00. | 0.762 |
| KXA30370.1 | hypE | HMPREF3229_00831 | HMPREF3229_00832 | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: tep:TepRe1_0239 2.7e-55 Thiamine-phosphate kinase; Psort location: Cytoplasmic, score: 7.50. | 0.773 |
| KXA30370.1 | lytC | HMPREF3229_00831 | HMPREF3229_00833 | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | KEGG: ccl:Clocl_1228 6.3e-45 N-acetylmuramoyl-L-alanine amidase; K01448 N-acetylmuramoyl-L-alanine amidase; Psort location: Cellwall, score: 8.28. | 0.568 |
| KXA30370.1 | outO | HMPREF3229_00831 | HMPREF3229_00830 | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | Bacterial peptidase A24 protein; KEGG: clj:CLJU_c05610 7.7e-35 bifunctional type IV leader peptidase/N-methyltransferase; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.773 |
| KXA30370.1 | smf | HMPREF3229_00831 | HMPREF3229_00824 | Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50. | DNA protecting protein DprA; KEGG: ccm:Ccan_01460 1.2e-43 protein smf K04096; Psort location: Cytoplasmic, score: 7.50. | 0.467 |
| KXA30374.1 | KXA30368.1 | HMPREF3229_00835 | HMPREF3229_00829 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Prepilin-type cleavage/methylation protein. | 0.579 |