STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lytCKEGG: ccl:Clocl_1228 6.3e-45 N-acetylmuramoyl-L-alanine amidase; K01448 N-acetylmuramoyl-L-alanine amidase; Psort location: Cellwall, score: 8.28. (448 aa)    
Predicted Functional Partners:
KXA30374.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
     0.801
rph
tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
       0.773
KXA30368.1
Prepilin-type cleavage/methylation protein.
  
  
 0.603
KXA30448.1
SpoIID/LytB domain protein; KEGG: bqy:MUS_3906 4.3e-29 lytC1; N-acetylmuramoyl-L-alanine amidase; Psort location: Cellwall, score: 8.75.
 
  
 0.585
hypE
Hypothetical protein; KEGG: tep:TepRe1_0239 2.7e-55 Thiamine-phosphate kinase; Psort location: Cytoplasmic, score: 7.50.
       0.584
outO
Bacterial peptidase A24 protein; KEGG: clj:CLJU_c05610 7.7e-35 bifunctional type IV leader peptidase/N-methyltransferase; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.582
epsF
Bacterial type II secretion system protein F domain protein; KEGG: pfe:PSF113_5005 5.4e-27 pilC; protein PilC K02653; Psort location: CytoplasmicMembrane, score: 10.00.
       0.573
KXA30370.1
Hypothetical protein; KEGG: fnu:FN0522 8.5e-07 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50.
       0.568
KXA29571.1
KEGG: bce:BC0902 7.1e-07 S-layer protein / N-acetylmuramoyl-L-alanine amidase K01448.
 
  
 0.518
penA
Penicillin-binding protein, transpeptidase domain protein; KEGG: aoe:Clos_1373 1.9e-118 peptidoglycan glycosyltransferase K08384; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.516
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.