Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
addAUvrD/REP helicase; ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. (975 aa)    
Predicted Functional Partners:
KXA31603.1
Hypothetical protein; KEGG: mvo:Mvol_0543 2.2e-06 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.975
bigR_2
Putative transcriptional repressor PagR; KEGG: apb:SAR116_2180 1.5e-06 ArsR family transcriptional regulator.
       0.737
KXA30410.1
butyryl-CoA:acetate CoA-transferase; KEGG: dat:HRM2_16060 1.9e-111 cat1; hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.709
recD
Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 
 0.677
KXA29990.1
KEGG: efc:EFAU004_00298 2.8e-22 Relaxase/mobilization nuclease domain protein; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.629
KXA29447.1
KEGG: efc:EFAU004_00298 5.0e-24 Relaxase/mobilization nuclease domain protein; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.629
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.586
dnaE
KEGG: txy:Thexy_0632 0. DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.540
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.479
pcrA
Putative ATP-dependent DNA helicase PcrA; KEGG: apr:Apre_0982 2.6e-176 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
 
   
0.477
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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