Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
porAKEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50. (1178 aa)    
Predicted Functional Partners:
ldh
KEGG: aur:HMPREF9243_0952 1.8e-60 L-lactate dehydrogenase K00016; Psort location: Cytoplasmic, score: 9.97; Belongs to the LDH/MDH superfamily.
  
 
 0.988
rnfB_2
Ferredoxin; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
 
 0.977
pyk
Pyruvate kinase; KEGG: csc:Csac_1831 1.4e-163 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50.
  
 0.974
pta
KEGG: lsl:LSL_1151 6.5e-102 pta; phosphate acetyltransferase K00625; Psort location: Cytoplasmic, score: 7.50.
   
 0.970
ppsA
Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.966
thlA
KEGG: apr:Apre_1351 5.6e-151 acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.961
KXA30812.1
KEGG: crn:CAR_c13520 1.1e-154 oadA; oxaloacetate decarboxylase subunit alpha K01571; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.958
cfiB
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.955
gcdB
glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
    
 0.932
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   0.932
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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