| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA30434.1 | KXA30437.1 | HMPREF3229_00897 | HMPREF3229_00900 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | 0.706 |
| KXA30434.1 | ffh | HMPREF3229_00897 | HMPREF3229_00898 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.935 |
| KXA30434.1 | rimM | HMPREF3229_00897 | HMPREF3229_00901 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.732 |
| KXA30434.1 | rplS | HMPREF3229_00897 | HMPREF3229_00903 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.673 |
| KXA30434.1 | rpsP | HMPREF3229_00897 | HMPREF3229_00899 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Ribosomal protein S16; KEGG: apb:SAR116_1817 9.2e-16 30S ribosomal protein S16 K02959; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bS16 family. | 0.754 |
| KXA30434.1 | trmD | HMPREF3229_00897 | HMPREF3229_00902 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.686 |
| KXA30437.1 | KXA30434.1 | HMPREF3229_00900 | HMPREF3229_00897 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.706 |
| KXA30437.1 | KXA30863.1 | HMPREF3229_00900 | HMPREF3229_00728 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | r3H domain protein; KEGG: sgg:SGGBAA2069_c20720 3.7e-19 jag; Jag family RNA-binding protein K06346; Psort location: Cytoplasmic, score: 7.50. | 0.985 |
| KXA30437.1 | ffh | HMPREF3229_00900 | HMPREF3229_00898 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.710 |
| KXA30437.1 | rimM | HMPREF3229_00900 | HMPREF3229_00901 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.929 |
| KXA30437.1 | rplS | HMPREF3229_00900 | HMPREF3229_00903 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.967 |
| KXA30437.1 | rpsD | HMPREF3229_00900 | HMPREF3229_00819 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.762 |
| KXA30437.1 | rpsO | HMPREF3229_00900 | HMPREF3229_01152 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.760 |
| KXA30437.1 | rpsP | HMPREF3229_00900 | HMPREF3229_00899 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | Ribosomal protein S16; KEGG: apb:SAR116_1817 9.2e-16 30S ribosomal protein S16 K02959; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bS16 family. | 0.961 |
| KXA30437.1 | rpsT | HMPREF3229_00900 | HMPREF3229_01271 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.701 |
| KXA30437.1 | trmD | HMPREF3229_00900 | HMPREF3229_00902 | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.859 |
| KXA30863.1 | KXA30437.1 | HMPREF3229_00728 | HMPREF3229_00900 | r3H domain protein; KEGG: sgg:SGGBAA2069_c20720 3.7e-19 jag; Jag family RNA-binding protein K06346; Psort location: Cytoplasmic, score: 7.50. | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | 0.985 |
| ffh | KXA30434.1 | HMPREF3229_00898 | HMPREF3229_00897 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.935 |
| ffh | KXA30437.1 | HMPREF3229_00898 | HMPREF3229_00900 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | KH domain protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0109 family. | 0.710 |
| ffh | rimM | HMPREF3229_00898 | HMPREF3229_00901 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.784 |