STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: faa:HMPREF0389_00596 1.8e-122 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 9.97. (511 aa)    
Predicted Functional Partners:
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; KEGG: tte:TTE2546 4.7e-99 MurF; UDP-N-acetylmuramyl pentapeptide synthase; K01929 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Psort location: Cytoplasmic, score: 9.95.
 
0.996
murD
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
0.990
penA
Penicillin-binding protein, transpeptidase domain protein; KEGG: aoe:Clos_1373 1.9e-118 peptidoglycan glycosyltransferase K08384; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.917
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 
 0.895
mraY_2
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.864
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
0.855
recJ
KEGG: cbe:Cbei_4321 1.8e-138 single-stranded-DNA-specific exonuclease RecJ; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.842
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.832
hemZ_1
Coproporphyrinogen dehydrogenase HemZ; KEGG: cce:Ccel_1948 2.3e-67 coproporphyrinogen III oxidase; K02495 oxygen-independent coproporphyrinogen III oxidase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.794
pbpA
Penicillin-binding protein, transpeptidase domain protein; KEGG: apr:Apre_0876 1.3e-89 peptidoglycan glycosyltransferase K05364; Psort location: CytoplasmicMembrane, score: 9.51.
 
  
 0.790
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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