Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
penAPenicillin-binding protein, transpeptidase domain protein; KEGG: aoe:Clos_1373 1.9e-118 peptidoglycan glycosyltransferase K08384; Psort location: CytoplasmicMembrane, score: 9.99. (823 aa)    
Predicted Functional Partners:
ftsW_2
Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
 
 0.993
mrcA
Transglycosylase; KEGG: apr:Apre_1213 6.8e-146 glycosyl transferase family protein; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.68.
 
 0.981
divIB
POTRA domain protein, FtsQ-type; Essential cell division protein.
 
 
 0.979
ftsW_1
Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
 
 0.975
murD
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
 0.974
mraY_2
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
 0.971
pbpD
Transglycosylase; KEGG: cst:CLOST_1328 5.7e-174 penicillin-binding protein, 1a family; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51.
 
0.966
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.961
KXA30469.1
Septum formation initiator; Psort location: CytoplasmicMembrane, score: 9.55.
  
 
 0.960
dacA-2
KEGG: apr:Apre_1285 2.3e-51 serine-type D-Ala-D-Ala carboxypeptidase K07258; Psort location: CytoplasmicMembrane, score: 8.78; Belongs to the peptidase S11 family.
 
 
 0.957
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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