| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| divIB | ftsW_2 | HMPREF3229_00938 | HMPREF3229_00936 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 0.957 |
| divIB | mraY_2 | HMPREF3229_00938 | HMPREF3229_00934 | POTRA domain protein, FtsQ-type; Essential cell division protein. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.884 |
| divIB | murC | HMPREF3229_00938 | HMPREF3229_00879 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.760 |
| divIB | murD | HMPREF3229_00938 | HMPREF3229_00935 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.955 |
| divIB | murE | HMPREF3229_00938 | HMPREF3229_00922 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: faa:HMPREF0389_00596 1.8e-122 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 9.97. | 0.608 |
| divIB | murF | HMPREF3229_00938 | HMPREF3229_00256 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; KEGG: tte:TTE2546 4.7e-99 MurF; UDP-N-acetylmuramyl pentapeptide synthase; K01929 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Psort location: Cytoplasmic, score: 9.95. | 0.760 |
| divIB | murG | HMPREF3229_00938 | HMPREF3229_00937 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.970 |
| divIB | penA | HMPREF3229_00938 | HMPREF3229_00933 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Penicillin-binding protein, transpeptidase domain protein; KEGG: aoe:Clos_1373 1.9e-118 peptidoglycan glycosyltransferase K08384; Psort location: CytoplasmicMembrane, score: 9.99. | 0.994 |
| divIB | rsmH | HMPREF3229_00938 | HMPREF3229_00931 | POTRA domain protein, FtsQ-type; Essential cell division protein. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.785 |
| ftsW_2 | divIB | HMPREF3229_00936 | HMPREF3229_00938 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | POTRA domain protein, FtsQ-type; Essential cell division protein. | 0.957 |
| ftsW_2 | mraY_2 | HMPREF3229_00936 | HMPREF3229_00934 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.969 |
| ftsW_2 | murAA | HMPREF3229_00936 | HMPREF3229_01533 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.779 |
| ftsW_2 | murC | HMPREF3229_00936 | HMPREF3229_00879 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.875 |
| ftsW_2 | murD | HMPREF3229_00936 | HMPREF3229_00935 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.979 |
| ftsW_2 | murE | HMPREF3229_00936 | HMPREF3229_00922 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: faa:HMPREF0389_00596 1.8e-122 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 9.97. | 0.692 |
| ftsW_2 | murF | HMPREF3229_00936 | HMPREF3229_00256 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; KEGG: tte:TTE2546 4.7e-99 MurF; UDP-N-acetylmuramyl pentapeptide synthase; K01929 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Psort location: Cytoplasmic, score: 9.95. | 0.771 |
| ftsW_2 | murG | HMPREF3229_00936 | HMPREF3229_00937 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.993 |
| ftsW_2 | penA | HMPREF3229_00936 | HMPREF3229_00933 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | Penicillin-binding protein, transpeptidase domain protein; KEGG: aoe:Clos_1373 1.9e-118 peptidoglycan glycosyltransferase K08384; Psort location: CytoplasmicMembrane, score: 9.99. | 0.993 |
| ftsW_2 | rsmH | HMPREF3229_00936 | HMPREF3229_00931 | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.799 |
| mraY_2 | divIB | HMPREF3229_00934 | HMPREF3229_00938 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | POTRA domain protein, FtsQ-type; Essential cell division protein. | 0.884 |