| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA28529.1 | polA | HMPREF3229_01767 | HMPREF3229_00450 | Hypothetical protein; KEGG: pel:SAR11G3_00965 1.9e-24 guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.512 |
| KXA28529.1 | rarA | HMPREF3229_01767 | HMPREF3229_00942 | Hypothetical protein; KEGG: pel:SAR11G3_00965 1.9e-24 guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase. | ATPase, AAA family; KEGG: ava:Ava_B0112 1.6e-105 recombination factor protein RarA/unknown domain fusion protein K07478; Psort location: Cytoplasmic, score: 7.50. | 0.542 |
| KXA28529.1 | relA | HMPREF3229_01767 | HMPREF3229_00918 | Hypothetical protein; KEGG: pel:SAR11G3_00965 1.9e-24 guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase. | Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.549 |
| KXA28529.1 | rsmB | HMPREF3229_01767 | HMPREF3229_00953 | Hypothetical protein; KEGG: pel:SAR11G3_00965 1.9e-24 guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.449 |
| asnS | gmk_2 | HMPREF3229_00943 | HMPREF3229_00946 | asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.680 |
| asnS | leuS | HMPREF3229_00943 | HMPREF3229_00944 | asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00. | leucine--tRNA ligase; KEGG: fma:FMG_0623 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.948 |
| asnS | nrdR | HMPREF3229_00943 | HMPREF3229_00941 | asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.646 |
| asnS | polA | HMPREF3229_00943 | HMPREF3229_00450 | asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.914 |
| asnS | rarA | HMPREF3229_00943 | HMPREF3229_00942 | asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00. | ATPase, AAA family; KEGG: ava:Ava_B0112 1.6e-105 recombination factor protein RarA/unknown domain fusion protein K07478; Psort location: Cytoplasmic, score: 7.50. | 0.665 |
| asnS | rsmB | HMPREF3229_00943 | HMPREF3229_00953 | asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.641 |
| gmk_2 | asnS | HMPREF3229_00946 | HMPREF3229_00943 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00. | 0.680 |
| gmk_2 | leuS | HMPREF3229_00946 | HMPREF3229_00944 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | leucine--tRNA ligase; KEGG: fma:FMG_0623 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.605 |
| gmk_2 | nrdR | HMPREF3229_00946 | HMPREF3229_00941 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.417 |
| gmk_2 | polA | HMPREF3229_00946 | HMPREF3229_00450 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.488 |
| gmk_2 | rarA | HMPREF3229_00946 | HMPREF3229_00942 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | ATPase, AAA family; KEGG: ava:Ava_B0112 1.6e-105 recombination factor protein RarA/unknown domain fusion protein K07478; Psort location: Cytoplasmic, score: 7.50. | 0.742 |
| gmk_2 | relA | HMPREF3229_00946 | HMPREF3229_00918 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.916 |
| gmk_2 | rsmB | HMPREF3229_00946 | HMPREF3229_00953 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.847 |
| leuS | asnS | HMPREF3229_00944 | HMPREF3229_00943 | leucine--tRNA ligase; KEGG: fma:FMG_0623 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00. | 0.948 |
| leuS | gmk_2 | HMPREF3229_00944 | HMPREF3229_00946 | leucine--tRNA ligase; KEGG: fma:FMG_0623 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.605 |
| leuS | nrdR | HMPREF3229_00944 | HMPREF3229_00941 | leucine--tRNA ligase; KEGG: fma:FMG_0623 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.561 |