Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gmk_2Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
 
 0.961
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
 0.946
KXA30482.1
TIGR00255 family protein; KEGG: pfe:PSF113_5769 1.5e-29 yicC; protein YicC; Psort location: Cytoplasmic, score: 7.50.
 
    0.941
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.924
gmk_1
Putative guanylate kinase; KEGG: sul:SYO3AOP1_0874 5.9e-21 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.97.
  
  
 
0.924
relA
Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.917
hpt_1
KEGG: ccb:Clocel_2100 3.0e-49 hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.916
hpt_2
KEGG: tva:TVAG_243770 5.0e-63 hypoxanthine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.916
nrdA
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.913
nrdB
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
   
 
 0.907
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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