Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXA30512.1KEGG: sdg:SDE12394_07245 1.6e-89 tRNA (uracil-5-)-methyltransferase; K03215 23S rRNA (uracil1939-C5)-methyltransferase; Psort location: Cytoplasmic, score: 7.50; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (518 aa)    
Predicted Functional Partners:
cvfB
S1 RNA binding domain protein; KEGG: mai:MICA_2002 8.5e-29 3-deoxy-7-phosphoheptulonate synthase K00243; Psort location: Cytoplasmic, score: 7.50; Belongs to the CvfB family.
  
    0.784
KXA30510.1
Hypothetical protein; KEGG: cno:NT01CX_0432 0.0040 gatC; aspartyl/glutamyl-tRNA amidotransferase subunit C; K02435 aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit C.
       0.773
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.737
lysS
lysine--tRNA ligase; KEGG: fma:FMG_0987 2.5e-251 lysyl-tRNA synthetase class II; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.544
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
    0.504
KXA30509.1
VanW-like protein; KEGG: mru:mru_1319 1.2e-05 DEAD/DEAH box helicase domain-containing protein; K03725 archaea-specific helicase.
       0.475
rsmI
S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
  
 0.452
rpsA
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
    0.447
KXA30507.1
Hypothetical protein; KEGG: adg:Adeg_1704 3.0e-10 adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.446
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.445
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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