| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA30522.1 | KXA31363.1 | HMPREF3229_00985 | HMPREF3229_00477 | Hypothetical protein. | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | 0.560 |
| KXA30522.1 | apt | HMPREF3229_00985 | HMPREF3229_01884 | Hypothetical protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.476 |
| KXA30522.1 | polA | HMPREF3229_00985 | HMPREF3229_00450 | Hypothetical protein. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.407 |
| KXA30522.1 | topA | HMPREF3229_00985 | HMPREF3229_00825 | Hypothetical protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.433 |
| KXA30522.1 | whiA | HMPREF3229_00985 | HMPREF3229_00293 | Hypothetical protein. | Hypothetical protein; Involved in cell division and chromosome segregation. | 0.499 |
| KXA30522.1 | xpt | HMPREF3229_00985 | HMPREF3229_00421 | Hypothetical protein. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.476 |
| KXA31363.1 | KXA30522.1 | HMPREF3229_00477 | HMPREF3229_00985 | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein. | 0.560 |
| KXA31363.1 | apt | HMPREF3229_00477 | HMPREF3229_01884 | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.598 |
| KXA31363.1 | xpt | HMPREF3229_00477 | HMPREF3229_00421 | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.598 |
| apt | KXA30522.1 | HMPREF3229_01884 | HMPREF3229_00985 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypothetical protein. | 0.476 |
| apt | KXA31363.1 | HMPREF3229_01884 | HMPREF3229_00477 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | comF family protein; KEGG: ccm:Ccan_18380 1.7e-14 protein COM101A; Psort location: Cytoplasmic, score: 7.50. | 0.598 |
| apt | polA | HMPREF3229_01884 | HMPREF3229_00450 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.443 |
| apt | xpt | HMPREF3229_01884 | HMPREF3229_00421 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.922 |
| polA | KXA30522.1 | HMPREF3229_00450 | HMPREF3229_00985 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Hypothetical protein. | 0.407 |
| polA | apt | HMPREF3229_00450 | HMPREF3229_01884 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.443 |
| polA | topA | HMPREF3229_00450 | HMPREF3229_00825 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.950 |
| polA | xpt | HMPREF3229_00450 | HMPREF3229_00421 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.443 |
| topA | KXA30522.1 | HMPREF3229_00825 | HMPREF3229_00985 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Hypothetical protein. | 0.433 |
| topA | polA | HMPREF3229_00825 | HMPREF3229_00450 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.950 |
| whiA | KXA30522.1 | HMPREF3229_00293 | HMPREF3229_00985 | Hypothetical protein; Involved in cell division and chromosome segregation. | Hypothetical protein. | 0.499 |