STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topB_3KEGG: apr:Apre_1822 3.7e-296 DNA topoisomerase type IA central domain-containing protein; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97. (577 aa)    
Predicted Functional Partners:
porA
KEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50.
  
   0.894
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.836
hhaIM_2
KEGG: aur:HMPREF9243_0159 1.1e-156 dcm; DNA (cytosine-5-)-methyltransferase K00558; Psort location: Cytoplasmic, score: 7.50.
       0.794
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.791
KXA31589.1
DEAD2 domain protein; KEGG: cno:NT01CX_0936 6.3e-175 hypothetical protein; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 7.50.
  
 0.751
asnS
asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00.
  
 
 0.696
KXA29536.1
Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50.
  
 0.693
sbcD
Ser/Thr phosphatase family protein; KEGG: sax:USA300HOU_1836 3.9e-24 sbcD; DNA repair exonuclease; Psort location: Cytoplasmic, score: 7.50.
  
 0.693
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.682
KXA29978.1
Copper amine oxidase domain protein; KEGG: ddi:DDB_G0274493 2.7e-11 lig1; DNA ligase I; K10747 DNA ligase 1; Psort location: Cytoplasmic, score: 9.67.
 
 
 0.601
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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