Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
topB_2KEGG: seq:SZO_12820 7.2e-245 DNA topoisomerase; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97. (568 aa)    
Predicted Functional Partners:
porA
KEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50.
  
   0.805
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.779
KXA31589.1
DEAD2 domain protein; KEGG: cno:NT01CX_0936 6.3e-175 hypothetical protein; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 7.50.
  
 0.713
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.692
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.612
KXA29441.1
Abortive infection protein AbiGI family protein; Psort location: Cytoplasmic, score: 7.50.
       0.582
KXA29442.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.580
KXA29536.1
Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50.
   
 0.537
sbcD
Ser/Thr phosphatase family protein; KEGG: sax:USA300HOU_1836 3.9e-24 sbcD; DNA repair exonuclease; Psort location: Cytoplasmic, score: 7.50.
   
 0.537
KXA29439.1
Copper amine oxidase domain protein; KEGG: bbe:BBR47_04720 0.0023 cwlU; hypothetical protein; K01448 N-acetylmuramoyl-L-alanine amidase.
  
 
 0.495
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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