Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdeAKEGG: bfr:BF3545 2.3e-168 O-acetylhomoserine (thiol)-lyase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.67. (426 aa)    
Predicted Functional Partners:
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.979
metK_2
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.923
msrC
KEGG: pfc:PflA506_1782 1.0e-32 yebR; free methionine-(R)-sulfoxide reductase YebR K07170; Psort location: Cytoplasmic, score: 7.50.
    
  0.903
hom_2
KEGG: fma:FMG_0319 2.7e-158 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.899
cysK
KEGG: apr:Apre_0955 1.6e-80 cysteine synthase A; K01738 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.874
tdcB_2
KEGG: apr:Apre_1062 8.6e-107 threonine dehydratase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 7.50.
  
 
  0.811
tdcB_1
Pyridoxal-phosphate dependent protein; KEGG: hbu:Hbut_0216 8.4e-61 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 7.50.
  
 
  0.811
cysE
KEGG: cow:Calow_1932 2.5e-52 serine o-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97.
    
 0.664
metE
KEGG: pdn:HMPREF9137_0954 3.6e-101 methionine synthase, vitamin-B12 independent; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.658
gltD
Glutamate synthase; KEGG: clj:CLJU_c37240 2.7e-261 glutamate synthase K00266; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.635
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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