Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
cssSATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ssr:SALIVB_0669 1.7e-48 sivK; sensor protein; Psort location: CytoplasmicMembrane, score: 9.96. (436 aa)    
Predicted Functional Partners:
regX3_1
Putative sensory transduction protein RegX3; KEGG: pmj:P9211_01481 5.6e-32 two-component response regulator K11329; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.968
KXA29483.1
Hypothetical protein; KEGG: pif:PITG_23229 0.0038 NADH dehydrogenase subunit 2, putative; K03879 NADH-ubiquinone oxidoreductase chain 2; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.890
ecsA_3
Putative bacitracin ABC transporter, ATP-binding protein BcrA; KEGG: ppo:PPM_1418 1.2e-54 ccmA3; multidrug ABC transporter ATPase K09687; Psort location: CytoplasmicMembrane, score: 8.78.
 
 
   0.877
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.732
lon1
Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
 0.689
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.673
phoB
Response regulator receiver domain protein; KEGG: pme:NATL1_11471 4.1e-29 phoB; two-component response regulator, phosphate K07657; Psort location: Cytoplasmic, score: 9.67.
 
 
 0.671
KXA31551.1
KEGG: bce:BC0902 3.8e-09 S-layer protein / N-acetylmuramoyl-L-alanine amidase K01448; Psort location: Cellwall, score: 9.39.
 
   
 0.660
phoP_1
Putative alkaline phosphatase synthesis transcriptional regulatory protein PhoP; KEGG: ava:Ava_1878 4.3e-41 two component transcriptional regulator K11329; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.645
KXA29986.1
Putative transcriptional regulatory protein afsQ1; KEGG: pmg:P9301_12431 5.5e-41 phoB; two-component response regulator, phosphate K07657; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.628
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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