Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ftsW_1Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. (421 aa)    
Predicted Functional Partners:
pbpA
Penicillin-binding protein, transpeptidase domain protein; KEGG: apr:Apre_0876 1.3e-89 peptidoglycan glycosyltransferase K05364; Psort location: CytoplasmicMembrane, score: 9.51.
 
 0.999
penA
Penicillin-binding protein, transpeptidase domain protein; KEGG: aoe:Clos_1373 1.9e-118 peptidoglycan glycosyltransferase K08384; Psort location: CytoplasmicMembrane, score: 9.99.
 
 0.975
KXA29499.1
FHA domain protein; KEGG: tel:tll2410 2.7e-08 adenylate cyclase; K01768 adenylate cyclase.
 
   
 0.943
ftsW_2
Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
  
  
 
0.927
divIB
POTRA domain protein, FtsQ-type; Essential cell division protein.
  
 
 0.922
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.863
KXA30492.1
Putative serine/threonine phosphatase stp; KEGG: crn:CAR_c09770 9.4e-46 prpC; phosphorylated protein phosphatase K01090.
 
  
 0.852
KXA30469.1
Septum formation initiator; Psort location: CytoplasmicMembrane, score: 9.55.
  
 
 0.837
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
     0.807
KXA31188.1
Septum formation initiator.
   
 
 0.805
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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