| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA29499.1 | ftsW_1 | HMPREF3229_01123 | HMPREF3229_01124 | FHA domain protein; KEGG: tel:tll2410 2.7e-08 adenylate cyclase; K01768 adenylate cyclase. | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 0.942 |
| KXA29499.1 | glpX | HMPREF3229_01123 | HMPREF3229_01129 | FHA domain protein; KEGG: tel:tll2410 2.7e-08 adenylate cyclase; K01768 adenylate cyclase. | Fructose-1,6-bisphosphatase, class II; KEGG: aoe:Clos_2595 1.9e-104 glpX; fructose 1,6-bisphosphatase II; K02446 fructose-1,6-bisphosphatase II; Psort location: Cytoplasmic, score: 9.97. | 0.783 |
| KXA29499.1 | ispD | HMPREF3229_01123 | HMPREF3229_01126 | FHA domain protein; KEGG: tel:tll2410 2.7e-08 adenylate cyclase; K01768 adenylate cyclase. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.781 |
| KXA29499.1 | ispF | HMPREF3229_01123 | HMPREF3229_01127 | FHA domain protein; KEGG: tel:tll2410 2.7e-08 adenylate cyclase; K01768 adenylate cyclase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.781 |
| KXA29499.1 | pbpA | HMPREF3229_01123 | HMPREF3229_01125 | FHA domain protein; KEGG: tel:tll2410 2.7e-08 adenylate cyclase; K01768 adenylate cyclase. | Penicillin-binding protein, transpeptidase domain protein; KEGG: apr:Apre_0876 1.3e-89 peptidoglycan glycosyltransferase K05364; Psort location: CytoplasmicMembrane, score: 9.51. | 0.932 |
| KXA29499.1 | tal | HMPREF3229_01123 | HMPREF3229_01128 | FHA domain protein; KEGG: tel:tll2410 2.7e-08 adenylate cyclase; K01768 adenylate cyclase. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.785 |
| divIB | ftsW_1 | HMPREF3229_00938 | HMPREF3229_01124 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 0.797 |
| divIB | ftsW_2 | HMPREF3229_00938 | HMPREF3229_00936 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Putative stage V sporulation protein E; KEGG: pfe:PSF113_4784 1.4e-51 ftsW; protein FtsW K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 0.957 |
| divIB | murC | HMPREF3229_00938 | HMPREF3229_00879 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.760 |
| divIB | murD | HMPREF3229_00938 | HMPREF3229_00935 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.955 |
| divIB | pbpA | HMPREF3229_00938 | HMPREF3229_01125 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Penicillin-binding protein, transpeptidase domain protein; KEGG: apr:Apre_0876 1.3e-89 peptidoglycan glycosyltransferase K05364; Psort location: CytoplasmicMembrane, score: 9.51. | 0.958 |
| ftsW_1 | KXA29499.1 | HMPREF3229_01124 | HMPREF3229_01123 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | FHA domain protein; KEGG: tel:tll2410 2.7e-08 adenylate cyclase; K01768 adenylate cyclase. | 0.942 |
| ftsW_1 | divIB | HMPREF3229_01124 | HMPREF3229_00938 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | POTRA domain protein, FtsQ-type; Essential cell division protein. | 0.797 |
| ftsW_1 | glpX | HMPREF3229_01124 | HMPREF3229_01129 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | Fructose-1,6-bisphosphatase, class II; KEGG: aoe:Clos_2595 1.9e-104 glpX; fructose 1,6-bisphosphatase II; K02446 fructose-1,6-bisphosphatase II; Psort location: Cytoplasmic, score: 9.97. | 0.781 |
| ftsW_1 | ispD | HMPREF3229_01124 | HMPREF3229_01126 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.792 |
| ftsW_1 | ispF | HMPREF3229_01124 | HMPREF3229_01127 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.792 |
| ftsW_1 | murC | HMPREF3229_01124 | HMPREF3229_00879 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.867 |
| ftsW_1 | murD | HMPREF3229_01124 | HMPREF3229_00935 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.805 |
| ftsW_1 | pbpA | HMPREF3229_01124 | HMPREF3229_01125 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | Penicillin-binding protein, transpeptidase domain protein; KEGG: apr:Apre_0876 1.3e-89 peptidoglycan glycosyltransferase K05364; Psort location: CytoplasmicMembrane, score: 9.51. | 0.999 |
| ftsW_1 | tal | HMPREF3229_01124 | HMPREF3229_01128 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.833 |