STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpXFructose-1,6-bisphosphatase, class II; KEGG: aoe:Clos_2595 1.9e-104 glpX; fructose 1,6-bisphosphatase II; K02446 fructose-1,6-bisphosphatase II; Psort location: Cytoplasmic, score: 9.97. (321 aa)    
Predicted Functional Partners:
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 0.970
fda
KEGG: faa:HMPREF0389_00042 1.2e-100 fructose-bisphosphate aldolase, class I; K01623 fructose-bisphosphate aldolase, class I.
    
 0.915
tal
Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
     
 0.848
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
       0.793
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.791
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
       0.790
KXA29499.1
FHA domain protein; KEGG: tel:tll2410 2.7e-08 adenylate cyclase; K01768 adenylate cyclase.
       0.783
ftsW_1
Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cpy:Cphy_1337 6.0e-51 penicillin-binding protein transpeptidase; K05364 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
       0.781
pbpA
Penicillin-binding protein, transpeptidase domain protein; KEGG: apr:Apre_0876 1.3e-89 peptidoglycan glycosyltransferase K05364; Psort location: CytoplasmicMembrane, score: 9.51.
       0.780
leuS
leucine--tRNA ligase; KEGG: fma:FMG_0623 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
    0.574
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.