| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA29536.1 | dnaN | HMPREF3229_01160 | HMPREF3229_00723 | Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.689 |
| KXA29536.1 | dut | HMPREF3229_01160 | HMPREF3229_01154 | Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50. | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.696 |
| KXA29536.1 | pgsA | HMPREF3229_01160 | HMPREF3229_01157 | Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50. | KEGG: apr:Apre_0617 1.3e-46 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.781 |
| KXA29536.1 | recA | HMPREF3229_01160 | HMPREF3229_01159 | Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.965 |
| KXA29536.1 | rimO | HMPREF3229_01160 | HMPREF3229_01156 | Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50. | Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.770 |
| KXA29536.1 | spoIIIE | HMPREF3229_01160 | HMPREF3229_01155 | Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50. | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 4.0e-109 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | 0.785 |
| KXA29536.1 | yfaY | HMPREF3229_01160 | HMPREF3229_01158 | Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 5.6e-13 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family. | 0.804 |
| coaBC | dut | HMPREF3229_00948 | HMPREF3229_01154 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.964 |
| dnaN | KXA29536.1 | HMPREF3229_00723 | HMPREF3229_01160 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50. | 0.689 |
| dnaN | dut | HMPREF3229_00723 | HMPREF3229_01154 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.725 |
| dnaN | nrdA | HMPREF3229_00723 | HMPREF3229_00747 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.763 |
| dnaN | recA | HMPREF3229_00723 | HMPREF3229_01159 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.926 |
| dnaN | spoIIIE | HMPREF3229_00723 | HMPREF3229_01155 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 4.0e-109 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | 0.529 |
| dut | KXA29536.1 | HMPREF3229_01154 | HMPREF3229_01160 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Ser/Thr phosphatase family protein; KEGG: bce:BC1857 2.3e-49 exonuclease SbcD K03547; Psort location: Cytoplasmic, score: 7.50. | 0.696 |
| dut | coaBC | HMPREF3229_01154 | HMPREF3229_00948 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.964 |
| dut | dnaN | HMPREF3229_01154 | HMPREF3229_00723 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.725 |
| dut | nrdA | HMPREF3229_01154 | HMPREF3229_00747 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.811 |
| dut | pgsA | HMPREF3229_01154 | HMPREF3229_01157 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | KEGG: apr:Apre_0617 1.3e-46 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.704 |
| dut | recA | HMPREF3229_01154 | HMPREF3229_01159 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.838 |
| dut | rimO | HMPREF3229_01154 | HMPREF3229_01156 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.680 |